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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PDCD4, programmed cell death 4 (neoplastic transformation inhibitor)
Sequence ID:NM_001199492
Entrez Gene ID:27250
Ensembl ID:ENSG00000150593

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 112631685 - 112658395

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4798293Full LengthBC026104programmed cell death 4 (neoplastic transformation inhibitor)
5277621Full LengthBC031049programmed cell death 4 (neoplastic transformation inhibitor)
3921489IncompleteBC015036programmed cell death 4 (neoplastic transformation inhibitor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055271  NP_663314  

Protein Infomation

NM_001199492 NP_001186421    
NM_014456 NP_055271 Q53EL6 MA3
NM_145341 NP_663314   MA3

Related Sequences

U96628 AAB67706 Q53EL6
BC015036 AAH15036 Q53EL6
BC026104 AAH26104 Q53EL6
BC031049 AAH31049 Q53EL6
DQ891645 ABM82571  
DQ894834 ABM85760  
AK223623 BAD97343 Q53EL6
AK312540 BAG35439 B2R6E2
AK315295 BAG37701 B2RCV4
AK296753 BAG59336 B4DKX4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PDCD4 NP_055271 M.musculus Pdcd4 18569 Gene Info NP_001161963 97
R.norvegicus Pdcd4 64031   NP_071601 97
A.gambiae AgaP_AGAP000378 1271876   XP_310731 50
D.melanogaster CG10990 32337   NP_001096977 41
A.thaliana AT5G63190 836440   NP_568968 33
A.thaliana AT4G24800 828582   NP_001031708 32
P.falciparum PF14_0546 812128   XP_001348720 25

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)