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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PAICS, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Sequence ID:NM_001079524
NM_001079525
NM_006452
Entrez Gene ID:10606
Ensembl ID:ENSG00000128050

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:Unknown

 Exon Info From UCSC:
NM_001079524
NM_001079525
NM_006452

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900848Full LengthBC010273phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
3533684Full LengthBC019255phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001079524 NP_001072992      
NM_001079525 NP_001072993      
NM_006452 NP_006443 P22234 EC 4.1.1.21
EC 6.3.2.6
AIRC
SAICAR_synt

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC010273 AAH10273 P22234 EC 4.1.1.21
EC 6.3.2.6
BC019255 AAH19255 P22234 EC 4.1.1.21
EC 6.3.2.6
BT006988 AAP35634 P22234 EC 4.1.1.21
EC 6.3.2.6
DQ893056 ABM83982    
DQ893776 ABM84702    
DQ896305 ABM87304    
DQ890605 ABM92222    
D28431 BAA05797    
AK294821 BAG57934 B4DGX3  
X53793 CAA37801 P22234 EC 4.1.1.21
EC 6.3.2.6
CR749824 CAH18683 P22234 EC 4.1.1.21
EC 6.3.2.6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAICS NP_001072993 R.norvegicus Paics 140946   NP_543186 96
M.musculus Paics 67054 Gene Info NP_080215 95
D.melanogaster ade5 32228   NP_572826 59
A.gambiae AgaP_AGAP000180 1272084   XP_310955 58
C.elegans B0286.3 173772   NP_494771 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)