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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NOS2, nitric oxide synthase 2, inducible
Sequence ID:NM_000625
NM_153292
RefSeqGene ID:NG_011470
Entrez Gene ID:4843
Ensembl ID:ENSG00000007171

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERTENSIONADD1
AGT
AGTR1
AGTR1
ATP1B1
ATP1B1
CYP3A5
ECE1
GNB3
NOS3
PTGIS
RGS5
RGS5
SELE
MALARIA, CEREBRALCD36
CISH
CR1
DARC
FCGR2B
GYPA
GYPC
ICAM1
SLC4A1
TIRAP
TNF

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q11.2-q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 26084271 - 26125835


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052646Full LengthBC144126nitric oxide synthase 2, inducible
40146314Full LengthBC130283nitric oxide synthase 2, inducible

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000616  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000625 NP_000616 P35228 EC 1.14.13.39 NAD_binding_1
Flavodoxin_1
FAD_binding_1
NO_synthase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L24553 AAA36375 P35228 EC 1.14.13.39
U05810 AAA56666 P35228 EC 1.14.13.39
L09210 AAA59171 P35228 EC 1.14.13.39
U31511 AAB49041 P35228 EC 1.14.13.39
U20141 AAB60366 P35228 EC 1.14.13.39
AF068236 AAC19133 P35228 EC 1.14.13.39
S75615 AAD14179 P35228 EC 1.14.13.39
S76479 AAD14226 Q9UM94  
BC130283 AAI30284 P35228 EC 1.14.13.39
BC144126 AAI44127 P35228 EC 1.14.13.39
HQ258688 ADR83439    
D26525 BAA05531 P35228 EC 1.14.13.39
AB022318 BAA37123 P35228 EC 1.14.13.39
AK304252 BAG65119 B4E2F7  
X73029 CAA51512 P35228 EC 1.14.13.39

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NOS2 NP_000616 M.musculus Nos2 18126 Gene Info NP_035057 81
R.norvegicus Nos2 24599   NP_036743 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta