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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DBT, dihydrolipoamide branched chain transacylase E2
Sequence ID:NM_001918
RefSeqGene ID:NG_011852
Entrez Gene ID:1629
Ensembl ID:ENSG00000137992

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MAPLE SYRUP URINE DISEASE, TYPE IABCKDHA
BCKDHB
DLD

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 100652477 - 100654537

 Exon Info From UCSC:
NM_001918

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3924492Full LengthBC016675dihydrolipoamide branched chain transacylase E2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001909  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001918 NP_001909 P11182 EC 2.3.1.168 2-oxoacid_dh
Biotin_lipoyl
E3_binding

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03208 AAA35589 P11182 EC 2.3.1.168
M19301 AAA59200 P11182 EC 2.3.1.168
M27093 AAA64512 P11182 EC 2.3.1.168
BC016675 AAH16675 P11182 EC 2.3.1.168
BT007372 AAP36036 P11182 EC 2.3.1.168
AK313191 BAG36008 P11182 EC 2.3.1.168
AK303941 BAG64869 B4E1Q7  
X66785 CAA47285 P11182 EC 2.3.1.168

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DBT NP_001909 M.musculus Dbt 13171 Gene Info NP_034152 88
R.norvegicus Dbt 29611   NP_445764 88
A.gambiae AgaP_AGAP000549 1271675   XP_310535 57
C.elegans ZK669.4 174279   NP_495670 57
D.melanogaster CG5599 32441   NP_573000 53
N.crassa NCU02704 3881627   XP_965477 47
A.thaliana BCE2 819869   NP_187341 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)