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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PABPN1, poly(A) binding protein, nuclear 1
Sequence ID:NM_004643
RefSeqGene ID:NG_008239
Entrez Gene ID:8106
Ensembl ID:ENSG00000100836

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 23791017 - 23793988

NM_004643 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4333442Full LengthBC010939poly(A) binding protein, nuclear 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004634  

Protein Infomation

NM_001199864 NP_001186793    
NM_004643 NP_004634 Q86U42 RRM_1

Related Sequences

BC010939 AAH10939 Q86U42
AK293633 BAG57089 B4DEH8
BX247976 CAD62310 Q86U42

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PABPN1 NP_004634 M.musculus Pabpn1 54196 Gene Info NP_062275 98
R.norvegicus Pabpn1 116697   NP_001128480 98
A.gambiae AgaP_AGAP005117 1274794   XP_313998 65
D.melanogaster Pabp2 35788   NP_476902 62
C.elegans pabp-2 172768   NP_492504 56
A.thaliana PABN1 835186   NP_568751 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta