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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. POLG, polymerase (DNA directed), gamma
Sequence ID:NM_001126131
RefSeqGene ID:NG_008218
Entrez Gene ID:5428
Ensembl ID:ENSG00000140521

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 89859533 - 89864133

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4384475Full LengthBC042571polymerase (DNA directed), gamma
6042595Full LengthBC050559polymerase (DNA directed), gamma

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002684  

Protein Infomation

NM_001126131 NP_001119603      
NM_002693 NP_002684 P54098 EC DNA_pol_A

Related Sequences

U60325 AAC50712 P54098 EC
BC042571 AAH42571 P54098 EC
BC050559 AAH50559 P54098 EC
D84103 BAA12223 P54098 EC
AK291281 BAF83970 A8K5G6  
X98093 CAA66719 P54098 EC

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens POLG NP_001119603 M.musculus Polg 18975 Gene Info NP_059490 88
R.norvegicus Polg 85472   NP_445980 87
D.melanogaster tam 34792   NP_476821 50
A.gambiae AgaP_AGAP000139 1272128   XP_311006 50
S.cerevisiae MIP1 854508   NP_014975 45
N.crassa NCU00276 3873917   XP_957747 45
S.pombe pog1 2539099   NP_588025 45

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)