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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TET2, tet methylcytosine dioxygenase 2
Sequence ID:NM_001127208
NM_017628
RefSeqGene ID:NG_028191
Entrez Gene ID:54790
Ensembl ID:ENSG00000168769

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
WOLFRAM-LIKE SYNDROME, AUTOSOMAL DOMINANTWFS1
WFS1

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 106182914 - 106200958

 Exon Info From UCSC:
NM_001127208
NM_017628

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40029091IncompleteBC110509tet oncogene family member 2
40029094IncompleteBC110510tet oncogene family member 2

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001127208 NP_001120680 Q6N021 EC 1.14.11.n2  
NM_017628 NP_060098 Q6N021 EC 1.14.11.n2  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC110509 AAI10510 Q6N021 EC 1.14.11.n2
BC110510 AAI10511 Q6N021 EC 1.14.11.n2
BC150180 AAI50181 A7E237  
BC150201 AAI50202 A7E237  
AK000039 BAA90898 Q6N021 EC 1.14.11.n2
AB046766 BAB13372 Q6N021 EC 1.14.11.n2
AK027819 BAB55391 Q6N021 EC 1.14.11.n2
AB075496 BAE45750 Q6N021 EC 1.14.11.n2
BX640738 CAE45851 Q6N021 EC 1.14.11.n2
FM992369 CAX30492 Q6N021 EC 1.14.11.n2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TET2 NP_001120680 R.norvegicus Tet2 310859   XP_227694 65
M.musculus Tet2 214133 Gene Info NP_001035490 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)