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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PTPLB, protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
Sequence ID:NM_198402
Entrez Gene ID:201562
Ensembl ID:ENSG00000206527

Database Links

UniGeneEntrez GeneEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 123210401 - 123211680

NM_198402 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1455123213362123213816
456634123219361123219539
635756123221406123221527
757845123247232123247320
846864123286608123286626
865982123301058123301175
9831187123303719123303923

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5273705Full LengthBC060839protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
5286864Full LengthBC049369protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
4398482IncompleteBC016990protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_940684  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_198402 NP_940684 Q6Y1H2 EC 4.2.1.134 PTPLA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC049369 AAH49369 Q6Y1H2 EC 4.2.1.134
BC060839 AAH60839 Q6Y1H2 EC 4.2.1.134
AY191814 AAP20101 Q6Y1H2 EC 4.2.1.134
AK289983 BAF82672 Q6Y1H2 EC 4.2.1.134

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTPLB NP_940684 M.musculus Ptplb 70757 Gene Info NP_076076 95
R.norvegicus Ptplb 288058   XP_213610 94
C.elegans T15B7.2 188513   NP_504740 46
A.gambiae AgaP_AGAP003814 1271554   XP_310375 43
A.thaliana PAS2 830912   NP_001190277 43
D.melanogaster CG6746 34614   NP_609534 40
S.pombe SPBC19C2.15c 2540685   NP_595700 38
N.crassa NCU08985 3875170   XP_959013 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)