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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CIITA, class II, major histocompatibility complex, transactivator
Sequence ID:NM_000246
RefSeqGene ID:NG_009628
Entrez Gene ID:4261
Ensembl ID:ENSG00000179583

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BARE LYMPHOCYTE SYNDROME, TYPE II, COMPLEMENTATION GROUP CRFX5
RFXANK
RFXANK
RFXAP
MULTIPLE SCLEROSISCD24
HLA-DQB1
HLA-DQB1
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL7R
PDCD1
PTPRC
RHEUMATOID ARTHRITISCD244
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL10
NFKBIL1
PADI4
PTPN22
RUNX1
RUNX1
SLC22A4
STAT4
STAT4

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 10971069 - 11018294

 Exon Info From UCSC:
NM_000246

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069042Full LengthBC172348class II, major histocompatibility complex, transactivator

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000237  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000246 NP_000237 P33076 NACHT

Related Sequences

 
mRNAGenPeptSwissProt
U18259 AAA88861 P33076
U18288 AAA88862 Q29675
U31931 AAA92364 Q29704
BC172348 AAI72348  
AF410154 AAL04118 Q96KL4
AY084054 AAM15723 Q8SNB8
AY084055 AAM15724 Q8SNB7
AY699071 AAU06586 Q66X48
X74301 CAA52354 P33076

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CIITA NP_000237 M.musculus Ciita 12265 Gene Info NP_031601 74
R.norvegicus Ciita 85483   NP_445981 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)