Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CFB, complement factor B
Sequence ID:NM_001710
RefSeqGene ID:NG_008191
Entrez Gene ID:629
Ensembl ID:ENSG00000243649

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AGE-RELATED MACULOPATHYAPOE
C2
CFHR1
CFHR3
CX3CR1
HMCN1
PLEKHA1
PLEKHA1
TLR3
HEMOLYTIC UREMIC SYNDROME, ATYPICAL 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31913791 - 31919860

 Exon Info From UCSC:
NM_001710

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2959705Full LengthBC004143complement factor B
2959706Full LengthBC007990complement factor B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001701  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001710 NP_001701 P00751 EC 3.4.21.47 Sushi
Trypsin
VWA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L15702 AAA16820 P00751 EC 3.4.21.47
J00185 AAA36219 P00751 EC 3.4.21.47
J00186 AAA36220 P00751 EC 3.4.21.47
K01566 AAA36225 P00751 EC 3.4.21.47
J00126 AAA36226 P00751 EC 3.4.21.47
S67310 AAD13989 P00751 EC 3.4.21.47
BC004143 AAH04143 P00751
Q53F89
EC 3.4.21.47
BC007990 AAH07990 P00751
Q53F89
EC 3.4.21.47
AF349679 AAK30167 P00751 EC 3.4.21.47
DQ892313 ABM83239    
DQ895516 ABM86442    
AK223400 BAD97120 Q53F89  
AK304042 BAG64953 B4E1Z1  
X00284 CAA25077 P00751 EC 3.4.21.47
X72875 CAA51389 P00751 EC 3.4.21.47

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CFB NP_001701 R.norvegicus Cfb 294257   NP_997631 85
M.musculus Cfb 14962 Gene Info NP_032224 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta