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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. FBXW8, F-box and WD repeat domain containing 8
Sequence ID:NM_012174
Entrez Gene ID:26259
Ensembl ID:ENSG00000174989

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q24.22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 117348782 - 117466168

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4821240Full LengthBC037296F-box and WD repeat domain containing 8
5296775IncompleteBC045190F-box and WD-40 domain protein 8

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_036306  NP_699179  

Protein Infomation

NM_012174 NP_036306   WD40
NM_153348 NP_699179 Q8N3Y1 WD40

Related Sequences

AF176707 AAF03129 Q8N3Y1
BC037296 AAH37296 Q8N3Y1
AK289621 BAF82310 A8K0Q6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens FBXW8 NP_699179 M.musculus Fbxw8 231672 Gene Info NP_766309 79
R.norvegicus Fbxw8 304522   NP_001100615 78

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)