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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GLA, Galactosidase, alpha
Sequence ID:NM_000169
RefSeqGene ID:NG_007119
Entrez Gene ID:2717
Ensembl ID:ENSG00000102393

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
FABRY DISEASE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 100652790 - 100662913

NM_000169 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1309100652778100653086
310507100653357100653554
508669100653772100653933
670761100655653100655744
762939100656619100656796
9401114100658798100658972
11151418100662697100663000

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3609235Full LengthBC002689galactosidase, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000160  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000169 NP_000160 Q53Y83
P06280
EC 3.2.1.22 Melibiase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002689 AAH02689 Q53Y83
P06280
EC 3.2.1.22
BT006864 AAP35510 Q53Y83
P06280
EC 3.2.1.22
DQ890721 ABM81647    
DQ893899 ABM84825    
D00039 BAA34059 Q6LER7  
AK222627 BAD96347 Q53HF3  
AK291095 BAF83784 Q53Y83  
AK297148 BAG59647 B4DLT5  
X05790 CAA29232 Q53Y83
P06280
EC 3.2.1.22

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GLA NP_000160 M.musculus Gla 11605 Gene Info NP_038491 78
R.norvegicus Gla 363494   NP_001102290 77
A.gambiae AgaP_AGAP009621 1278996   XP_318652 50
D.melanogaster CG5731 34355   NP_609354 49
A.thaliana AGAL2 830735   NP_568193 47
C.elegans gana-1 179660   NP_506031 44
S.pombe mel1 2543243   NP_595012 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)