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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SPHK1, sphingosine kinase 1
Sequence ID:NM_001142601
NM_001142602
NM_021972
NM_182965
Entrez Gene ID:8877
Ensembl ID:ENSG00000176170

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 74381707 - 74383667

 Exon Info From UCSC:
NM_001142601
NM_001142602
NM_021972
NM_182965

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3506924Full LengthBC009419sphingosine kinase 1
3831657Full LengthBC008040sphingosine kinase 1
4871343Full LengthBC014439sphingosine kinase 1
5213270Full LengthBC030553sphingosine kinase 1
3832587IncompleteBC004112sphingosine kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_068807  NP_892010  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001142601 NP_001136073 Q9NYA1 EC 2.7.1.91  
NM_001142602 NP_001136074      
NM_021972 NP_068807 Q96GK1   DAGK_cat
NM_182965 NP_892010     DAGK_cat

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF238083 AAF73423 Q9NYA1 EC 2.7.1.91
AF266756 AAF73470 Q9NYA1
Q53ZR5
EC 2.7.1.91
AF200328 AAG01980 Q9NYA1 EC 2.7.1.91
BC004112 AAH04112 Q9BTG7  
BC008040 AAH08040 Q96HV8  
BC009419 AAH09419 Q96GK1  
BC014439 AAH14439 Q9NYA1 EC 2.7.1.91
BC030553 AAH30553 Q9NYA1 EC 2.7.1.91
AK022402 BAB14028 Q9NYA1
Q53ZR5
EC 2.7.1.91
AK023393 BAB14558 Q9NYA1
Q53ZR5
EC 2.7.1.91
AK292294 BAF84983 Q9NYA1 EC 2.7.1.91
AK292614 BAF85303 Q53ZR5  
AK122781 BAG53725 B3KVB3  
AJ245504 CAB92131 Q9NYA1 EC 2.7.1.91

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SPHK1 NP_892010 M.musculus Sphk1 20698 Gene Info NP_001165943 81
R.norvegicus Sphk1 170897   NP_596877 79
A.thaliana SPHK1 828239   NP_193885 39
A.thaliana AT4G21534 10723114   NP_001190787 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta