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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. RASA1, RAS p21 protein activator (GTPase activating protein) 1
Sequence ID:NM_002890
NM_022650
RefSeqGene ID:NG_011650
Entrez Gene ID:5921
Ensembl ID:ENSG00000145715

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
BASAL CELL CARCINOMA, SOMATICPTCH1
PTCH2
CAPILLARYMALFORMATION-ARTERIOVENOUS MALFORMATION 
PARKES WEBER SLNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 86564069 - 86686744

 Exon Info From UCSC:
NM_002890
NM_022650

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4829173Full LengthBC033015RAS p21 protein activator (GTPase activating protein) 1
4733187IncompleteBC020761RAS p21 protein activator (GTPase activating protein) 1
6663865IncompleteBC054891RAS p21 protein activator (GTPase activating protein) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002881  NP_072179  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002890 NP_002881 P20936 SH2
SH3_1
C2
PH
RasGAP
NM_022650 NP_072179   SH2
SH3_1
C2
PH
RasGAP
SH3_2

Related Sequences

 
mRNAGenPeptSwissProt
M23612 AAA35865 P20936
M23379 AAA52517 P20936
BC020761 AAH20761 Q05CU5
BC033015 AAH33015 P20936
BC054891 AAH54891 Q7Z4M2
AB209106 BAD92343 Q59GK3
AK312739 BAG35610 P20936
AK300263 BAG62024 B4DTL2
AK300269 BAG62030 B4DTL8
AK300406 BAG62136 B4DTX4
CR749722 CAH18488 Q68CU6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RASA1 NP_002881 M.musculus Rasa1 218397 Gene Info NP_663427 96
R.norvegicus Rasa1 25676   NP_037267 96
D.melanogaster vap 32569   NP_523361 49
A.gambiae AgaP_AGAP002729 1273239   XP_312197 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta