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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CDKL5, cyclin-dependent kinase-like 5
Sequence ID:NM_001037343
NM_003159
RefSeqGene ID:NG_008475
Entrez Gene ID:6792
Ensembl ID:ENSG00000008086

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ANGELMAN SYNDROMEMECP2
MECP2
UBE3A
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1ARX
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 2 
RETT SYNDROMEMECP2
MECP2

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 18605805 - 18607935

 Exon Info From UCSC:
NM_001037343
NM_003159

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100016109BC152846cyclin-dependent kinase-like 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003150  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001037343 NP_001032420 O76039 EC 2.7.11.22  
NM_003159 NP_003150 O76039 EC 2.7.11.22 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC152846 AAI52847    
AY217744 AAO64440 O76039 EC 2.7.11.22
HQ171445 ADN38258 O76039 EC 2.7.11.22
X89059 CAA61445 O76039 EC 2.7.11.22
Y15057 CAA75342 O76039 EC 2.7.11.22

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDKL5 NP_001032420 M.musculus Cdkl5 382253 Gene Info NP_001019795 96
R.norvegicus LOC100362725 100362725   XP_002730278 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)