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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. APEX2, APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Sequence ID:NM_001271748
NM_014481
RefSeqGene ID:NG_012568
Entrez Gene ID:27301
Ensembl ID:ENSG00000169188

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 55026795 - 55034200

Transcript StartTranscript EndChromosomal Start Chromosomal End
12335502677955027011
2343175502797855028061
3184985502868355028863
4996455502939455029540
6467155503023155030300
71619765503295055034210

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3537317Full LengthBC002959APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055296  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001271748 NP_001258677      
NM_014481 NP_055296 Q9UBZ4 EC 4.2.99.18 Exo_endo_phos
zf-GRF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF119046 AAD43041 Q9UBZ4 EC 4.2.99.18
BC002959 AAH02959 Q9UBZ4 EC 4.2.99.18
DQ893669 ABM84595    
DQ895556 ABM86482    
AB021260 BAA78422 Q9UBZ4 EC 4.2.99.18
AB049211 BAB13764 Q9UBZ4 EC 4.2.99.18
AK301555 BAG63051 B4DWI9  
AK316186 BAH14557 B7ZA71  
AJ011311 CAB45242 Q9UBZ4 EC 4.2.99.18

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens APEX2 NP_055296 M.musculus Apex2 77622 Gene Info NP_084219 80
R.norvegicus RGD1565983 317628   NP_001073361 80
A.thaliana AT4G36050 829761   NP_974691 42
N.crassa NCU01961 3880490   XP_964325 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)