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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. LGR5, leucine-rich repeat containing G protein-coupled receptor 5
Sequence ID:NM_003667
Entrez Gene ID:8549
Ensembl ID:ENSG00000139292

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 71833860 - 71978514

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40008253Full LengthBC096324leucine-rich repeat-containing G protein-coupled receptor 5
40008255Full LengthBC096325leucine-rich repeat-containing G protein-coupled receptor 5
40008256Full LengthBC099650leucine-rich repeat-containing G protein-coupled receptor 5
40008257Full LengthBC096326leucine-rich repeat-containing G protein-coupled receptor 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003658  

Protein Infomation

NM_003667 NP_003658 O75473 LRR_1

Related Sequences

AF062006 AAC28019 O75473
AF061444 AAC77911 O75473
BC096324 AAH96324 O75473
BC096325 AAH96325 O75473
BC096326 AAH96326 O75473
BC099650 AAH99650 O75473
AK294985 BAG58053 B4DH92

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens LGR5 NP_003658 M.musculus Lgr5 14160   NP_034325 86
R.norvegicus Lgr5 299802   NP_001100254 86
A.gambiae GPRRK 1277636   XP_317111 34
D.melanogaster rk 34819   NP_476702 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)