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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LRP2, Low density lipoprotein receptor-related protein 2
Sequence ID:NM_004525
RefSeqGene ID:NG_012634
Entrez Gene ID:4036
Ensembl ID:ENSG00000081479

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DONNAI-BARROW SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q24-q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 170097259 - 170219044

 Exon Info From UCSC:
NM_004525

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004516  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004525 NP_004516 P98164 EGF
Ldl_recept_a
Ldl_recept_b
EGF_CA
EGF_2

Related Sequences

 
mRNAGenPeptSwissProt
U04441 AAB02882 P98164
S73145 AAB30825 P98164
U33837 AAB41649 P98164
AY265357 AAP88585 Q7Z5C1
AY265358 AAP88586 Q7Z5C0
AK295005 BAG58066 B4DHA5
AK302843 BAG64033 B4DZC1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LRP2 NP_004516 R.norvegicus Lrp2 29216   NP_110454 77
M.musculus Lrp2 14725 Gene Info NP_001074557 77
D.melanogaster Megalin 8674055   NP_001096924 44
A.gambiae AgaP_AGAP000331 1271927   XP_310784 44
C.elegans lrp-1 172520   NP_492127 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)