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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TLR3, toll-like receptor 3
Sequence ID:NM_003265
RefSeqGene ID:NG_007278
Entrez Gene ID:7098
Ensembl ID:ENSG00000164342

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AGE-RELATED MACULOPATHYAPOE
C2
CFB
CFHR1
CFHR3
CX3CR1
HMCN1
PLEKHA1
PLEKHA1

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 186997773 - 187006027

NM_003265 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
194186990308186990401
95542186997766186998213
543734186999993187000184
7352587187003473187005325
25883039187005798187006249

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
30531515Full LengthBC094737toll-like receptor 3
40008349Full LengthBC096333toll-like receptor 3
40008350Full LengthBC096334toll-like receptor 3
40008351Full LengthBC096335toll-like receptor 3
5294919IncompleteBC043204toll-like receptor 3
30337077IncompleteBC059372toll-like receptor 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003256  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003265 NP_003256 O15455 LRR_1
TIR

Related Sequences

 
mRNAGenPeptSwissProt
U88879 AAC34134 O15455
BC059372 AAH59372 Q6PCD4
BC094737 AAH94737 Q504W0
BC096333 AAH96333 O15455
BC096334 AAH96334 O15455
BC096335 AAH96335 O15455
DQ445682 ABE01399 O15455
DQ470075 ABF06633 Q1KMK2
DQ470076 ABF06634 Q1KMK2
DQ470077 ABF06635 Q1KMK2
DQ470078 ABF06636 Q1KMK2
DQ470079 ABF06637 Q1KMK2
AK314208 BAG36884 B2RAI7
AB445631 BAG55028 O15455
AK302143 BAH13636 B7Z7K0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TLR3 NP_003256 R.norvegicus Tlr3 364594   NP_942086 81
M.musculus Tlr3 142980 Gene Info NP_569054 80

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta