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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ITPR3, Inositol 1,4,5-trisphosphate receptor, type 3
Sequence ID:NM_002224
RefSeqGene ID:NG_027729
Entrez Gene ID:3710
Ensembl ID:ENSG00000096433

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, INSULIN-DEPENDENTFOXP3
HLA-DQB1
HLA-DQB1
HNF1A
OAS1
PTPN22
SH2B3

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 33631311 - 33664338

 Exon Info From UCSC:
NM_002224

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100069100Full LengthBC172406inositol 1,4,5-triphosphate receptor, type 3
40147135IncompleteBC146646inositol 1,4,5-triphosphate receptor, type 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002215  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002224 NP_002215 Q14573 Ion_trans
RYDR_ITPR
MIR
RIH_assoc

Related Sequences

 
mRNAGenPeptSwissProt
U01062 AAC50064 Q14573
BC146646 AAI46647 A6H8K3
BC172406 AAI72406  
D26351 BAA05385 Q14573
AB209739 BAD92976 Q59ES2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ITPR3 NP_002215 M.musculus Itpr3 16440 Gene Info NP_542120 95
R.norvegicus Itpr3 25679   NP_037270 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)