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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ARFGEF1, ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Sequence ID:NM_006421
Entrez Gene ID:10565
Ensembl ID:ENSG00000066777

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 68085746 - 68179679

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100068937BC172243ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006412  

Protein Infomation

NM_006421 NP_006412 Q9Y6D6 Sec7

Related Sequences

AF084520 AAD38427 Q9Y6D6
AF111162 AAD43651 Q9Y6D6
BC172243 AAI72243  
AK001788 BAA91912 Q9Y6D6
AB209324 BAD92561 Q59FY5
AK022557 BAG51091 B3KMS9
AL117446 CAB55931 Q9Y6D6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ARFGEF1 NP_006412 M.musculus Arfgef1 211673 Gene Info NP_001095900 97
R.norvegicus Arfgef1 312915   XP_232614 97
A.gambiae AgaP_AGAP008906 1279872   XP_319652 71
D.melanogaster sec71 34785   NP_609675 68
C.elegans agef-1 173231   NP_001129800 50
A.thaliana EDA10 839301   NP_171698 40
N.crassa NCU07658 3878933   XP_962785 38
A.thaliana AT3G60860 825257   NP_191645 37
S.pombe sec71 2543610   NP_594954 36
S.pombe sec72 2542107   NP_594555 35
S.cerevisiae SEC7 851748   NP_010454 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta