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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PAK3, p21 protein (Cdc42/Rac)-activated kinase 3
Sequence ID:NM_001128166
NM_001128167
NM_001128168
NM_001128172
NM_001128173
NM_002578
RefSeqGene ID:NG_008288
Entrez Gene ID:5063
Ensembl ID:ENSG00000077264

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, X-LINKED 30/47 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 110366331 - 110463675

 Exon Info From UCSC:
NM_001128166
NM_001128167
NM_001128168
NM_001128172
NM_001128173
NM_002578

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40125904IncompleteBC117353p21 (CDKN1A)-activated kinase 3
40125906IncompleteBC117355p21 (CDKN1A)-activated kinase 3
100016002BC152761p21 protein (Cdc42/Rac)-activated kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002569  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001128166 NP_001121638    
NM_001128167 NP_001121639    
NM_001128168 NP_001121640    
NM_001128172 NP_001121644    
NM_001128173 NP_001121645    
NM_002578 NP_002569   Pkinase
PBD
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF068864 AAC36097 O75914 EC 2.7.11.1
AF155651 AAF67008 O75914 EC 2.7.11.1
BC152761 AAI52762    
AB102659 BAC81128 O75914 EC 2.7.11.1
AK290504 BAF83193 O75914 EC 2.7.11.1
AK315284 BAG37693 B2RCU6  
AM943850 CAQ16016 O75914 EC 2.7.11.1
AM943851 CAQ16017 O75914 EC 2.7.11.1
AM943852 CAQ16018 O75914 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PAK3 NP_001121640 R.norvegicus Pak3 29433   NP_062083 99
M.musculus Pak3 18481 Gene Info NP_032804 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta