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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2AK4, eukaryotic translation initiation factor 2 alpha kinase 4
Sequence ID:NM_001013703
Entrez Gene ID:440275
Ensembl ID:ENSG00000128829

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 40246114 - 40327791

 Exon Info From UCSC:
NM_001013703

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4137621IncompleteBC009350eukaryotic translation initiation factor 2 alpha kinase 4
6504179IncompleteBC061591eukaryotic translation initiation factor 2 alpha kinase 4
100015174BC146319eukaryotic translation initiation factor 2 alpha kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001013725  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001013703 NP_001013725 Q9P2K8 EC 2.7.11.1 Pkinase
RWD
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC009350 AAH09350 Q9P2K8 EC 2.7.11.1
BC078179 AAH78179 Q9P2K8 EC 2.7.11.1
BC146319 AAI46320 Q9P2K8 EC 2.7.11.1
AB037759 BAA92576 Q9P2K8 EC 2.7.11.1
AK027011 BAB15625 Q9P2K8 EC 2.7.11.1
AJ243428 CAB58360 Q9P2K8 EC 2.7.11.1
AL137627 CAB70849 Q9P2K8 EC 2.7.11.1
AL157497 CAB75678 Q9P2K8 EC 2.7.11.1
AL832907 CAH10626 Q9P2K8 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2AK4 NP_001013725 M.musculus Eif2ak4 27103 Gene Info NP_038747 91
D.melanogaster Gcn2 43709   NP_477230 36
S.pombe gcn2 2540500   NP_595991 32
N.crassa NCU01187 3877676   XP_961553 32
A.gambiae AgaP_AGAP012368 1280343   XP_320188 31
C.elegans Y81G3A.3 174953   NP_496781 30
S.cerevisiae GCN2 851877   NP_010569 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta