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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. LEFTY1, Left-right determination factor 1
Sequence ID:NM_020997
Entrez Gene ID:10637
Ensembl ID:ENSG00000243709

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1q42.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 226074079 - 226076836

NM_020997 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
33840226073982226074789
8411080226075098226075337
10811327226075485226075731
13281647226076516226076835

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5221120Full LengthBC027883left-right determination factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066277  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_020997 NP_066277 O75610 TGF_beta
TGFb_propeptide

Related Sequences

 
mRNAGenPeptSwissProt
AF081512 AAD48144 O75610
BC027883 AAH27883 O75610
AY358873 AAQ89232 O75610
DQ896626 ABM87625  
AK222714 BAD96434 O75610
AK313115 BAG35937 B2R7U0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LEFTY1 NP_066277 M.musculus Lefty1 13590 Gene Info NP_034224 82
R.norvegicus Lefty1 498299   NP_001102550 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)