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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MAP4K3, Mitogen-activated protein kinase kinase kinase kinase 3
Sequence ID:NM_003618
RefSeqGene ID:NG_028007
Entrez Gene ID:8491
Ensembl ID:ENSG00000011566

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 39476422 - 39487883

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5296205Full LengthBC071579mitogen-activated protein kinase kinase kinase kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003609  

Protein Infomation

NM_001270425 NP_001257354      
NM_003618 NP_003609 Q8IVH8 EC Pkinase

Related Sequences

BC071579 AAH71579 Q8IVH8 EC
EU832785 ACE87796    
GQ129258 ACT64392    
AK291467 BAF84156 A8K602  
AK021553 BAG51037 B3KMM5  
AK299889 BAG61735 B4DSS3  
AK316144 BAH14515 B7ZA29  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MAP4K3 NP_003609 M.musculus Map4k3 225028 Gene Info NP_001074826 96
R.norvegicus Map4k3 170920   NP_596898 96
D.melanogaster hppy 37203   NP_611399 65
A.gambiae AgaP_AGAP010837 1271122   XP_309868 61
C.elegans gck-2 179072   NP_504721 48

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta