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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PLCE1, Phospholipase C, epsilon 1
Sequence ID:NM_016341
NM_001165979
RefSeqGene ID:NG_015799
Entrez Gene ID:51196
Ensembl ID:ENSG00000138193

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NEPHROTIC SYNDROME, TYPE 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 95753745 - 96088146

 Exon Info From UCSC:
NM_016341
NM_001165979

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8860521Full LengthBC151854phospholipase C, epsilon 1
9021573Full LengthBC140705phospholipase C, epsilon 1
9052806Full LengthBC144286phospholipase C, epsilon 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057425  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001165979 NP_001159451      
NM_016341 NP_057425 Q9P212 EC 3.1.4.11 C2
PI-PLC-Y
PI-PLC-X
RasGEF
RA

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF117948 AAF22005 Q9P212 EC 3.1.4.11
AF190642 AAG17145 Q9P212 EC 3.1.4.11
AF170071 AAG28341 Q9P212 EC 3.1.4.11
BC140705 AAI40706 Q9P212 EC 3.1.4.11
BC144286 AAI44287 B7ZM61  
BC151854 AAI51855 Q9P212 EC 3.1.4.11
AY995135 AAY45890 Q9P212 EC 3.1.4.11
AB040949 BAA96040 Q9P212 EC 3.1.4.11
AK022543 BAB14090 Q9P212 EC 3.1.4.11
AK289852 BAF82541 Q9P212 EC 3.1.4.11
AK297779 BAG60124 B4DN62  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PLCE1 NP_057425 M.musculus Plce1 74055 Gene Info NP_062534 86
R.norvegicus Plce1 114633   NP_446210 85
A.gambiae AgaP_AGAP002529 1273433   XP_563634 42
C.elegans plc-1 181274   NP_001123141 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta