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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. EIF6, eukaryotic translation initiation factor 6
Sequence ID:NM_001267810
RefSeqGene ID:NG_023238
Entrez Gene ID:3692
Ensembl ID:ENSG00000242372

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 33866724 - 33872552

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823211Full LengthBC019305eukaryotic translation initiation factor 6
2989973Full LengthBC001119eukaryotic translation initiation factor 6
4120463Full LengthBC011845eukaryotic translation initiation factor 6
30559307IncompleteBC095465integrin beta 4 binding protein

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002203  NP_852133  NP_852131  

Protein Infomation

NM_001267810 NP_001254739    
NM_002212 NP_002203 P56537 eIF-6
NM_181466 NP_852131   eIF-6
NM_181468 NP_852133 P56537 eIF-6

Related Sequences

AF022229 AAB97735 P56537
AF047433 AAC39897 P56537
BC001119 AAH01119 P56537
BC011845 AAH11845 P56537
BC019305 AAH19305 P56537
DQ892592 ABM83518  
DQ895811 ABM86737  
AB062289 BAB93472 P56537
AK314969 BAG37470 P56537
AK296076 BAG58832 B4DJH0
Y11435 CAA72243 P56537
CR456764 CAG33045 P56537

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens EIF6 NP_002203 M.musculus Eif6 16418 Gene Info NP_034709 98
D.melanogaster eIF6 37776   NP_659573 78
A.gambiae AgaP_AGAP001380 1281798   XP_321758 77
S.pombe tif6 2539126   NP_588491 74
A.thaliana emb1624 824728   NP_191121 73
S.cerevisiae TIF6 856126   NP_015341 73
N.crassa NCU09004 3875154   XP_959032 72
C.elegans eif-6 173169   NP_493272 65
P.falciparum PF13_0178 814148   XP_001350059 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta