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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HBA2, hemoglobin, alpha 2
Sequence ID:NM_000517
RefSeqGene ID:NG_000006
Entrez Gene ID:3040
Ensembl ID:ENSG00000188536

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEINZ BODY ANEMIAHBA1
HBB
HEMOGLOBIN H DISEASE, NONDELETIONALHBA1
THALASSEMIA, ALPHA-HBA1
HBB

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 226694 - 227448

NM_000517 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1161222845223005
162366223123223327
367604223470223707

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000508  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000517 NP_000508 P69905 Globin
NM_000558 NP_000549 P69905 Globin

Related Sequences

 
mRNAGenPeptSwissProt
AF097635 AAC72839 P69905
AF105974 AAC97373 P69905
AF281258 AAF90195 Q9NQT3
BC005931 AAH05931 P69905
BC008572 AAH08572 P69905
BC032122 AAH32122 P69905
BC050661 AAH50661 P69905
BC101846 AAI01847 P69905
BC101848 AAI01849 P69905
AF349571 AAK37554 P69905
DQ891761 ABM82687  
DQ893109 ABM84035  
DQ894945 ABM85871  
DQ896383 ABM87382  
AK223392 BAD97112 P69905
V00493 CAA23752 P69905

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HBA2 NP_000508 H.sapiens HBA1 3039 Gene Info NP_000549 100
M.musculus Hba-a1 15122 Gene Info NP_032244 87
M.musculus Hba-a2 110257 Gene Info NP_001077424 87
R.norvegicus LOC360504 360504   NP_001007723 79
R.norvegicus Hba-a2 25632   NP_037228 78

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta