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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NUMB, numb homolog (Drosophila)
Sequence ID:NM_001005743
NM_001005744
NM_001005745
NM_003744
RefSeqGene ID:NG_029061
Entrez Gene ID:8650
Ensembl ID:ENSG00000133961

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 73742380 - 73925244

 Exon Info From UCSC:
NM_001005743
NM_001005744
NM_001005745
NM_003744

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4822300Full LengthBC068476numb homolog (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001005744  NP_001005745  NP_003735  NP_001005743  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001005743 NP_001005743 P49757 PID
NumbF
NM_001005744 NP_001005744   PID
NumbF
NM_001005745 NP_001005745   PID
NumbF
NM_003744 NP_003735   PID
NumbF

Related Sequences

 
mRNAGenPeptSwissProt
L40393 AAC42000 P49757
Q5D0E5
AF015040 AAD01548 P49757
AF108092 AAD27959 P49757
AF171938 AAD54279 P49757
AF171939 AAD54280 P49757
AF171940 AAD54281 P49757
AF171941 AAD54282 P49757
BC020788 AAH20788 P49757
BC033824 AAH33824 Q5D0E5
BC068476 AAH68476 P49757
EU265734 ABY89090 B1P2N5
EU265735 ABY89091 B1P2N6
EU265736 ABY89092 B1P2N7
EU265737 ABY89093 B1P2N8
EU265738 ABY89094 B1P2N9
JF432783 ADZ16000  
AK315130 BAG37583 B2RCI6
AK294591 BAG57779 B1P2N9
AK300602 BAG62299 B4DUD7
AK304193 BAG65073 P49757
BX248073 CAD62362 P49757
BX248775 CAD66582 Q86SW6
BX248781 CAD66588 Q86SW5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NUMB NP_001005743 M.musculus Numb 18222 Gene Info NP_001129547 94
R.norvegicus Numb 29419   NP_579821 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)