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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IL10RB, interleukin 10 receptor, beta
Sequence ID:NM_000628
RefSeqGene ID:NG_012089
Entrez Gene ID:3588
Ensembl ID:ENSG00000243646

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEPATITIS B VIRUSIFNAR2
IFNGR1
INFLAMMATORYBOWEL DISEASE 25, EARLY ONSET, AUTOSOMAL RECESSIVE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 34640232 - 34669258

NM_000628 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11483463867134638818
1492723464069834640821
2734303464890034649057
4315973465205634652222
5987453465539834655545
7469033466040834660565
90419353466848834669519

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3544611Full LengthBC001903interleukin 10 receptor, beta

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000628 NP_000619 Q08334  

Related Sequences

 
mRNAGenPeptSwissProt
BC001903 AAH01903 Q08334
BT009777 AAP88779 Q08334
DQ892552 ABM83478  
DQ895763 ABM86689  
JN591378 AEX60807 H2DF06
AK124057 BAC85761 Q6ZVU9
AK299961 BAG61787 B4DSX5
Z17227 CAA78933 Q08334

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL10RB NP_000619 R.norvegicus Il10rb 304091   NP_001100581 73
M.musculus Il10rb 16155 Gene Info NP_032375 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta