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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IRF2, interferon regulatory factor 2
Sequence ID:NM_002199
Entrez Gene ID:3660
Ensembl ID:ENSG00000168310

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q34.1-q35.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 185309911 - 185395704

NM_002199 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
191361185308877185310219
13621408185311856185311902
14091573185320068185320232
15741691185329311185329428
16921738185339320185339366
17391915185339685185339861
19162015185340622185340721
20162108185350131185350223
21092302185395532185395725

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3920890Full LengthBC015803interferon regulatory factor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002190  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002199 NP_002190 P14316 IRF

Related Sequences

 
mRNAGenPeptSwissProt
BC015803 AAH15803 P14316
BT007264 AAP35928 P14316
AK312953 BAG35793 P14316
X15949 CAA34073 P14316
CR457077 CAG33358 P14316

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IRF2 NP_002190 M.musculus Irf2 16363 Gene Info NP_032417 93
R.norvegicus Irf2 290749   NP_001040551 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta