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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PDE6B, phosphodiesterase 6B, cGMP-specific, rod, beta
Sequence ID:NM_000283
NM_001145291
NM_001145292
RefSeqGene ID:NG_009839
Entrez Gene ID:5158
Ensembl ID:ENSG00000133256

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NIGHT BLINDNESS, CONGENITAL STATIONARY, AUTOSOMAL DOMINANT 2 
RETINITIS PIGMENTOSA-40 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4p16.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 646968 - 664022

 Exon Info From UCSC:
NM_000283
NM_001145291
NM_001145292

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3356353Full LengthBC000249phosphodiesterase 6B, cGMP-specific, rod, beta
5301963IncompleteBC039412phosphodiesterase 6B, cGMP-specific, rod, beta (congenital stationary night blindness 3, autosomal dominant)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000274  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000283 NP_000274 P35913 EC 3.1.4.35 PDEase_I
GAF
NM_001145291 NP_001138763      
NM_001145292 NP_001138764      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S41458 AAB22690 P35913 EC 3.1.4.35
BC000249 AAH00249 P35913 EC 3.1.4.35
BT009794 AAP88796 P35913 EC 3.1.4.35
DQ895767 ABM86693    
EU176360 ABW03811    
AK295285 BAG58269 B4DHV7  
AK316054 BAH14425 B7Z9T9  
X66142 CAA46932 P35913 EC 3.1.4.35

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE6B NP_001138763 M.musculus Pde6b 18587 Gene Info NP_032832 94
R.norvegicus Pde6b 289878   NP_001099494 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta