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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NUP214, Nucleoporin 214kDa
Sequence ID:NM_005085
RefSeqGene ID:NG_023371
Entrez Gene ID:8021
Ensembl ID:ENSG00000126883

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKEMIA, ACUTE MYELOGENOUSARHGEF12
CBFB
CEBPA
CHIC2
ETV6
FLT3
GATA2
GMPS
JAK2
KIT
LPP
MLF1
MLLT10
NPM1
NSD1
PICALM
RUNX1
RUNX1
SH3GL1
TERT
WHSC1L1

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q34.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 134001088 - 134109090

 Exon Info From UCSC:
NM_005085

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5268515Full LengthBC045620nucleoporin 214kDa
30531438Full LengthBC105998nucleoporin 214kDa
4508050IncompleteBC012500nucleoporin 214kDa

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005085 NP_005076 P35658  

Related Sequences

 
mRNAGenPeptSwissProt
BC045620 AAH45620 P35658
BC105998 AAI05999 P35658
D14689 BAA03515 P35658
AB159230 BAD07398 P35658
AK302676 BAG63908 B4DYZ6
AK316417 BAH14788 B7ZAV2
AK316435 BAH14806 B7ZAX0
X64228 CAA45535 P35658
BX537986 CAD97946 Q7Z3C4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NUP214 NP_005076 M.musculus Nup214 227720 Gene Info NP_758472 79
R.norvegicus Nup214 296634   NP_001162031 79
D.melanogaster Nup214 46091   NP_652039 33
A.gambiae AgaP_AGAP008970 1279934   XP_319720 32
C.elegans npp-14 172813   NP_492568 28

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta