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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. FLG, filaggrin
Sequence ID:NM_002016
RefSeqGene ID:NG_016190
Entrez Gene ID:2312
Ensembl ID:ENSG00000143631

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DERMATITIS, ATOPIC, SUSCEPTIBILITYTO, 2 
ICHTHYOSIS VULGARIS 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 152278159 - 152279909

NM_002016 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
112573152274650152287222
1257412732152287794152287952
1273312747152297664152297678

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002007  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002016 NP_002007 P20930 S_100
Filaggrin

Related Sequences

 
mRNAGenPeptSwissProt
M24355 AAA52454 P20930
L01090 AAA60176 Q4JFL9
M60495 AAA63245 Q03837
M60499 AAA63246 Q03838
M60500 AAA63247 Q03839
M60502 AAA63248 Q16824
GU014833 ACX32320 P20930
AB208881 BAD92118 Q59H78

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FLG NP_002007 M.musculus Flg 14246 Gene Info XP_485270 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)