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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CYP21A2, cytochrome P450, family 21, subfamily A, polypeptide 2
Sequence ID:NM_000500
NM_001128590
RefSeqGene ID:NG_007941
Entrez Gene ID:1589
Ensembl ID:ENSG00000231852

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADRENAL HYPERPLASIA, CONGENITAL, DUE TO 21-HYDROXYLASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31973457 - 31976684

 Exon Info From UCSC:
NM_000500
NM_001128590

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40122017Full LengthBC125181cytochrome P450, family 21, subfamily A, polypeptide 2
40122018Full LengthBC125182cytochrome P450, family 21, subfamily A, polypeptide 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000491  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000500 NP_000491 Q16874   p450
NM_001128590 NP_001122062      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M17252 AAA59985 P08686 EC 1.14.99.10
BC125181 AAI25182 Q08AG9  
BC125182 AAI25183 P08686 EC 1.14.99.10
BC128535 AAI28536 A1A5B1  
AK054616 BAB70774 Q96NU8  
AK314651 BAG37212 Q16874  
AM086564 CAJ31103 Q2UVX6  
AM086565 CAJ31104 Q2UVX5  
AM183945 CAJ75799 Q1H8Y5  
AM183946 CAJ75800 Q1H8Y4  
AM183947 CAJ75801 Q1H8Y3  
AM183948 CAJ75802 Q1H8Y2  
AM183949 CAJ75803 Q1EM53  
AM183950 CAJ75804 Q1EM52  
AM183951 CAJ75805 Q1EM51  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CYP21A2 NP_000491 M.musculus Cyp21a1 13079 Gene Info NP_034125 73
R.norvegicus Cyp21a1 24298   NP_476442 71

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)