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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LIPC, lipase, hepatic
Sequence ID:NM_000236
RefSeqGene ID:NG_011465
Entrez Gene ID:3990
Ensembl ID:ENSG00000166035

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
HEPATIC LIPASE DEFICIENCY 
[HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QTL 12] 

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q21-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 58702774 - 58861072

NM_000236 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11455872417458724318
1463305883053158830715
3315135883398358834165
5146315883473258834849
6328655883794058838173
86611085884052858840770
110912265885306258853179
122714455885570358855921
144616035886091458861071

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9020484Full LengthBC136495lipase, hepatic
40146847Full LengthBC132825lipase, hepatic
40148028Full LengthBC146659lipase, hepatic

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000227  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000236 NP_000227 P11150 EC 3.1.1.3 Lipase
PLAT

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03540 AAA59520 P11150 EC 3.1.1.3
J03895 AAA61165 P11150 EC 3.1.1.3
BC132825 AAI32826 P11150 EC 3.1.1.3
BC136495 AAI36496 P11150 EC 3.1.1.3
BC146659 AAI46660 A6H8L5  
HQ258274 ADR83028    
D83548 BAA12014 P11150 EC 3.1.1.3
AK290062 BAF82751 A8K1Z7  
AK292631 BAF85320 P11150 EC 3.1.1.3
AK315306 BAG37710 P11150 EC 3.1.1.3
AK293324 BAG56842 B4DDT1  
X07228 CAA30188 P11150 EC 3.1.1.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LIPC NP_000227 R.norvegicus Lipc 24538   NP_036729 76
M.musculus Lipc 15450 Gene Info NP_032306 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)