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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DEFA3, defensin, alpha 3, neutrophil-specific
Sequence ID:NM_005217
Entrez Gene ID:1668
Ensembl ID:ENSG00000239839

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:8p23.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 6873390 - 6875803

NM_005217 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1224168733916873620
24242868741976874383
42950168757436875815

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5226993Full LengthBC027917defensin, alpha 3, neutrophil-specific
40117146Full LengthBC119706defensin, alpha 3, neutrophil-specific

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005208  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005217 NP_005208 P59666
Q6EZE9
Defensin_1
Defensin_propep

Related Sequences

 
mRNAGenPeptSwissProt
M21131 AAA35753 P59666
M23281 AAA52304 P59666
Q6EZE9
BC027917 AAH27917 P59666
Q6EZE9
BC119706 AAI19707 Q6EZE9
EU176174 ABW03625  
X13621 CAA31952 P59666
Q6EZE9

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DEFA3 NP_005208 H.sapiens DEFA1 1667 Gene Info NP_004075 99
H.sapiens DEFA1B 728358   NP_001035965 99

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)