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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSD, Cathepsin D
Sequence ID:NM_001909
RefSeqGene ID:NG_008655
Entrez Gene ID:1509
Ensembl ID:ENSG00000117984

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CEROID LIPOFUSCINOSIS, NEURONAL, 10 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.5Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 1773984 - 1785105

NM_001909 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
86100117739841774899
1002110017750321775130
1101124517752231775367
1246136817761351776257
1369160117785531778785
1602172017801981780316
1721184417807451780868
1845200417825381782697
2005220517850211785221

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3506977Full LengthBC016320cathepsin D

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001900  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001909 NP_001900 P07339 EC 3.4.23.5 Asp
A1_Propeptide

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M11233 AAB59529 P07339 EC 3.4.23.5
BC016320 AAH16320 P07339 EC 3.4.23.5
BT006910 AAP35556 P07339 EC 3.4.23.5
BT020155 AAV38957 P07339 EC 3.4.23.5
DQ893547 ABM84473    
DQ893878 ABM84804    
X05344 CAA28955 P07339 EC 3.4.23.5
CR456947 CAG33228 P07339 EC 3.4.23.5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSD NP_001900 R.norvegicus Ctsd 171293   NP_599161 83
M.musculus Ctsd 13033 Gene Info NP_034113 82
C.elegans asp-4 181444   NP_510191 60
A.gambiae AgaP_AGAP003277 1269179   XP_307784 59
D.melanogaster cathD 45268   NP_652013 56
A.thaliana AT4G04460 825776   NP_192355 50
N.crassa NCU02273 3876039   XP_959917 45
S.cerevisiae PEP4 855949   NP_015171 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta