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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IMPDH1, IMP (inosine 5'-monophosphate) dehydrogenase 1
Sequence ID:NM_000883
NM_001102605
NM_001142573
NM_001142574
NM_001142575
NM_001142576
NM_183243
RefSeqGene ID:NG_009194
Entrez Gene ID:3614
Ensembl ID:ENSG00000106348

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, pineal gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LEBER CONGENITAL AMAUROSIS 11 
RETINITIS PIGMENTOSA 10 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q31.3-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 128032331 - 128045996

 Exon Info From UCSC:
NM_000883
NM_001102605
NM_001142573
NM_001142574
NM_001142575
NM_001142576
NM_183243

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5210847Full LengthBC033622IMP (inosine monophosphate) dehydrogenase 1

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000883 NP_000874      
NM_001102605 NP_001096075      
NM_001142573 NP_001136045 P20839 EC 1.1.1.205  
NM_001142574 NP_001136046      
NM_001142575 NP_001136047      
NM_001142576 NP_001136048      
NM_183243 NP_899066      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J05272 AAA36114 P20839 EC 1.1.1.205
BC033622 AAH33622 P20839 EC 1.1.1.205
AK054640 BAB70780 P20839 EC 1.1.1.205
AK131294 BAD18464 Q6ZNB1  
AK054667 BAG51409 P20839 EC 1.1.1.205
AK092452 BAG52555 B3KRZ3  
AK122994 BAG53840 B3KVM8  
AK293413 BAG56920 P20839 EC 1.1.1.205
AK297943 BAG60259 B4DNJ7  
CR933672 CAI45968 Q5H9Q6  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IMPDH1 NP_000874 M.musculus Impdh1 23917 Gene Info NP_035959 98
R.norvegicus Impdh1 362329   NP_001102089 98
A.gambiae AgaP_AGAP011133 1270793   XP_309514 70
D.melanogaster ras 43873   NP_727441 70
S.cerevisiae IMD4 854948   NP_013656 64
S.cerevisiae IMD3 851152   NP_013536 63
S.cerevisiae IMD2 856626   NP_012088 62
N.crassa NCU03117 3881134   XP_964976 62
S.pombe gua1 2540315   NP_595702 61
C.elegans T22D1.3 177457   NP_001023395 59
P.falciparum PFI1020c 813484   XP_001352079 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)