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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. FAP, fibroblast activation protein, alpha
Sequence ID:NM_004460
RefSeqGene ID:NG_027991
Entrez Gene ID:2191
Ensembl ID:ENSG00000078098

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 163027194 - 163033179

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4731931Full LengthBC026250fibroblast activation protein, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004451  

Protein Infomation

NM_004460 NP_004451 Q12884 Peptidase_S9

Related Sequences

U09278 AAB49652 Q12884
U76833 AAC51668 Q12884
BC026250 AAH26250 Q12884
DQ891423 ABM82349  
DQ894597 ABM85523  
AK315448 BAG37836 B2RD89
AK297118 BAG59624 B4DLR2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens FAP NP_004451 M.musculus Fap 14089 Gene Info NP_032012 90
R.norvegicus Fap 192203   NP_620205 89
A.gambiae AgaP_AGAP011584 1271175   XP_309924 39
D.melanogaster ome 44297   NP_524739 36
S.pombe SPACUNK4.08 2542415   NP_593970 35
C.elegans dpf-2 181579   NP_510461 34
N.crassa NCU02515 3881844   XP_965646 34
S.cerevisiae DAP2 856423   NP_011893 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)