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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IGF1R, insulin-like growth factor 1 receptor
Sequence ID:NM_000875
NM_152452
RefSeqGene ID:NG_009492
Entrez Gene ID:3480
Ensembl ID:ENSG00000140443

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
INSULIN-LIKE GROWTH FACTOR I, RESISTANCE TO 

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q26.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 99192816 - 99193756


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8322662Full LengthBC113610insulin-like growth factor 1 receptor
8322664Full LengthBC113612insulin-like growth factor 1 receptor
9052235Full LengthBC143721insulin-like growth factor 1 receptor
4156235IncompleteBC010607insulin-like growth factor 1 receptor
40014689IncompleteBC107089insulin-like growth factor 1 receptor

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000875 NP_000866 P08069 EC 2.7.10.1 fn3
Furin-like
Recep_L_domain
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF020763 AAB97676 O43467  
BC107089 AAI07090 Q3B833  
BC113610 AAI13611 P08069 EC 2.7.10.1
BC113612 AAI13613 P08069 EC 2.7.10.1
BC143721 AAI43722    
EU826611 ACF47647    
EU826612 ACF47648    
AB425196 BAG11657 P08069 EC 2.7.10.1
X04434 CAA28030 P08069 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IGF1R NP_000866 M.musculus Igf1r 16001 Gene Info NP_034643 96
R.norvegicus Igf1r 25718   NP_434694 96
A.gambiae INR 1280455   XP_320130 46
D.melanogaster InR 42549   NP_001138094 42
C.elegans daf-2 175410   NP_497650 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta