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Gene Info

Gene Information For:Hs. AP1S2, adaptor-related protein complex 1, sigma 2 subunit
Sequence ID:NM_003916
RefSeqGene ID:NG_009274
Entrez Gene ID:8905
Ensembl ID:ENSG00000182287

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, X-LINKED SYNDROMIC, FRIED TYPE 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp22.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 15845264 - 15870647

NM_003916 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
215671584392915845494
156817051586350115863638
170618141586402515864133
181519931587046815870646
199422831587281015873099

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3050001Full LengthBC001117adaptor-related protein complex 1, sigma 2 subunit
4556064Full LengthBC071867adaptor-related protein complex 1, sigma 2 subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003907  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003916 NP_003907 P56377
Q549M9
Clat_adaptor_s

Related Sequences

 
mRNAGenPeptSwissProt
AF091077 AAC72946 P56377
AF251295 AAG44595 P56377
BC001117 AAH01117 P56377
Q549M9
BC071867 AAH71867 P56377
Q549M9
BT006738 AAP35384 P56377
Q549M9
AF087876 AAP97176 P56377
Q549M9
DQ890705 ABM81631  
DQ893889 ABM84815  
AB015320 BAA33392 P56377
Q549M9
AK299921 BAG61756 B4DSU4
AK296135 BAH12265 B7Z3M9
BX537780 CAD97839 Q7Z677

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AP1S2 NP_003907 R.norvegicus Ap1s2 302671   NP_001121003 100
M.musculus Ap1s2 108012 Gene Info NP_081163 99
D.melanogaster AP-1sigma 42835   NP_651198 83
A.gambiae AgaP_AGAP004283 1274441   XP_313555 81
C.elegans aps-1 178989   NP_504559 80
N.crassa NCU10618 5847413   XP_001728227 64
P.falciparum PF11_0187 810734   XP_001347858 61
A.thaliana AT4G35410 829694   NP_195267 60
A.thaliana AP19 816245   NP_565415 60
S.pombe SPAP27G11.06c 2542885   NP_593410 58
S.cerevisiae APS1 850868   NP_013271 55

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)