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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MDC1, mediator of DNA-damage checkpoint 1
Sequence ID:NM_014641
Entrez Gene ID:9656
Ensembl ID:ENSG00000137337

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 30672092 - 30685058

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9007258Full LengthBC152556mediator of DNA damage checkpoint 1
3897457IncompleteBC110645mediator of DNA damage checkpoint 1

Protein Infomation

NM_014641 NP_055456 Q14676  

Related Sequences

BC110645 AAI10646 Q14676
BC152556 AAI52557 Q14676
EF177820 ABM47418 A1Z5I6
EF177821 ABM47419 A1Z5I7
EF177822 ABM47420 A1Z5I8
EF177823 ABM47421 A1Z5I9
D79992 BAA11487 Q14676
AK298749 BAG60892 B4DQD0
AK302434 BAG63736 B4DYH4
CR749828 CAH18685 Q14676

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MDC1 NP_055456 M.musculus Mdc1 240087 Gene Info NP_001010833 55
R.norvegicus Mdc1 309595   NP_001159747 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)