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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NLRP1, NLR family, pyrin domain containing 1
Sequence ID:NM_001033053
NM_014922
NM_033004
NM_033006
NM_033007
RefSeqGene ID:NG_011651
Entrez Gene ID:22861
Ensembl ID:ENSG00000091592

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 5417441 - 5487799

 Exon Info From UCSC:
NM_001033053
NM_014922
NM_033004
NM_033006
NM_033007

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5756099Full LengthBC051787NLR family, pyrin domain containing 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055737  NP_127499  NP_127500  NP_127497  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001033053 NP_001028225    
NM_014922 NP_055737   LRR_1
CARD
PAAD_DAPIN
NACHT
AAA_5
NM_033004 NP_127497 Q9C000 LRR_1
CARD
PAAD_DAPIN
NACHT
NM_033006 NP_127499   LRR_1
CARD
PAAD_DAPIN
NACHT
AAA_5
NM_033007 NP_127500   LRR_1
CARD
PAAD_DAPIN
NACHT
AAA_5

Related Sequences

 
mRNAGenPeptSwissProt
AF298548 AAG15254 Q9C000
AF310105 AAG30288 Q9C000
AF229059 AAK00748 Q9C000
AF229060 AAK00749 Q9C000
AF229061 AAK00750 Q9C000
AF229062 AAK00751 Q9C000
AB023143 BAA76770 Q9C000
AK026393 BAB15469 Q9H5Z8
AK026398 BAB15470 Q9H5Z7
AL117470 CAB55945 Q9C000

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NLRP1 NP_127497 M.musculus Nlrp1a 195046 Gene Info NP_001004142 63
M.musculus Nlrp1b 637515 Gene Info NP_001155886 57
R.norvegicus Nlrp1b 691998   XP_001080760 56

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)