Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. BRK1, BRICK1, SCAR/WAVE actin-nucleating complex subunit
Sequence ID:NM_018462
Entrez Gene ID:55845
Ensembl ID:ENSG00000254999

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p25.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 10157378 - 10168601

NM_018462 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823162Full LengthBC001067chromosome 3 open reading frame 10
2823162Full LengthBC019303chromosome 3 open reading frame 10
3688264Full LengthBC007929chromosome 3 open reading frame 10
6500741IncompleteBC061515chromosome 3 open reading frame 10

Protein Infomation

NM_018462 NP_060932 Q8WUW1  

Related Sequences

AF161418 AAF28978 Q8WUW1
AF220047 AAF67640 Q9NZ47
BC001067 AAH01067 Q8WUW1
BC007929 AAH07929 Q8WUW1
BC019303 AAH19303 Q8WUW1
AY148219 AAN60161 Q8WUW1
AY148220 AAN60162 Q8WUW1
DQ892956 ABM83882  
DQ896203 ABM87202  
EU176410 ABW03861  
AK290580 BAF83269 Q9NZ47
AK312155 BAG35089 Q8WUW1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens BRK1 NP_060932 M.musculus 6720456B07Rik 101314 Gene Info NP_598698 99
R.norvegicus Brk1 679934   XP_001055004 99
D.melanogaster HSPC300 246497   NP_726400 77
A.gambiae AgaP_AGAP007614 1269615   XP_308258 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)