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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. EIF4B, eukaryotic translation initiation factor 4B
Sequence ID:NM_018507
Entrez Gene ID:1975
Ensembl ID:ENSG00000063046

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q13.13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 53410256 - 53434007

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6015183Full LengthBC073154eukaryotic translation initiation factor 4B
6459393Full LengthBC098437eukaryotic translation initiation factor 4B
6527540Full LengthBC073139eukaryotic translation initiation factor 4B
3507583IncompleteBC001097eukaryotic translation initiation factor 4B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001408  

Protein Infomation

NM_001417 NP_001408 P23588 RRM_1

Related Sequences

AF119854 AAF69608 Q9P192
BC001097 AAH01097 Q7Z5Y0
BC073139 AAH73139 P23588
BC073154 AAH73154 P23588
BC098437 AAH98437 P23588
AB076839 BAB82380 P23588
AK222528 BAD96248 P23588
AK312187 BAG35120 Q9P192
AK293731 BAG57157 B4DEP6
AK299329 BAG61335 B4DRM3
AK299510 BAG61463 B4DS01
AK299526 BAG61475 B4DS13
CR456958 CAG33239 P23588
CR627377 CAH10474 Q6AI40

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens EIF4B NP_001408 R.norvegicus Eif4b 300253   NP_001008325 96
M.musculus Eif4b 75705 Gene Info NP_663600 94
A.gambiae AgaP_AGAP000525 1271716   XP_310562 39
S.pombe sce3 2540528   NP_595728 37
N.crassa NCU00457 3872923   XP_956776 36
D.melanogaster eIF-4B 3355041   NP_001015319 35
S.cerevisiae TIF3 856292   NP_015489 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)