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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PDE5A, phosphodiesterase 5A, cGMP-specific
Sequence ID:NM_001083
NM_033430
NM_033437
Entrez Gene ID:8654
Ensembl ID:ENSG00000138735

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:4q27Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 120419723 - 120548336

 Exon Info From UCSC:
NM_001083
NM_033430
NM_033437

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
8991949Full LengthBC126233phosphodiesterase 5A, cGMP-specific

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_236914  NP_246273  NP_001074  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001083 NP_001074 O76074 EC 3.1.4.35 PDEase_I
GAF
NM_033430 NP_236914     PDEase_I
GAF
NM_033437 NP_246273     PDEase_I
GAF

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF043731 AAC63967 O76074 EC 3.1.4.35
AF043732 AAC63968 O76074 EC 3.1.4.35
AF155192 AAF40303 Q9P0K6  
AF155193 AAF40304 Q9P0K5  
AF155194 AAF40305    
BC126233 AAI26234 O76074 EC 3.1.4.35
AY264918 AAP21809 O76074 EC 3.1.4.35
AY266363 AAP31235 O76074 EC 3.1.4.35
JQ286346 AEW91484 I6NLS4  
AB015656 BAA81667 O76074 EC 3.1.4.35
AK290189 BAF82878 O76074 EC 3.1.4.35
AJ004865 CAA06170 O76074 EC 3.1.4.35
AM392687 CAL37565    
AM392735 CAL37613    
AM392945 CAL37823    
AM393036 CAL37914    
AM393171 CAL38049    
AM393270 CAL38148    
AM393311 CAL38189    
AM393426 CAL38304    
AM393432 CAL38310    
AM393448 CAL38326    
AM393814 CAL38689    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PDE5A NP_001074 M.musculus Pde5a 242202 Gene Info NP_700471 94
R.norvegicus Pde5a 171115   NP_598268 93
A.gambiae AgaP_AGAP008646 1275495   XP_314743 50
D.melanogaster Pde11 35107   NP_609885 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)