Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DARS2, Aspartyl-tRNA synthetase 2, mitochondrial
Sequence ID:NM_018122
RefSeqGene ID:NG_016138
Entrez Gene ID:55157
Ensembl ID:ENSG00000117593

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q25.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 173800701 - 173827559

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5273243Full LengthBC045173aspartyl-tRNA synthetase 2, mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_060592  

Protein Infomation

NM_018122 NP_060592 Q6PI48 EC tRNA-synt_2

Related Sequences

BC045173 AAH45173 Q6PI48 EC
AK001376 BAA91658 Q9NVT8  
AK022754 BAB14228 Q9H9J7  
AK290873 BAF83562 A8K4A8  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DARS2 NP_060592 M.musculus Dars2 226539 Gene Info NP_766232 86
R.norvegicus Dars2 304919   NP_001029315 86
A.gambiae AgaP_AGAP007844 1278116   XP_317655 50
D.melanogaster CG31739 326155   NP_724018 48
C.elegans drs-2 3565124   NP_506019 46
A.thaliana AT4G33760 829518   NP_195102 44
S.pombe SPCC736.06 2538918   NP_587777 41
S.cerevisiae MSD1 856000   NP_015221 39
N.crassa NCU02585 3881866   XP_965716 39

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)