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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MLL3, myeloid/lymphoid or mixed-lineage leukemia 3
Sequence ID:NM_170606
NM_021230
Entrez Gene ID:58508
Ensembl ID:ENSG00000055609

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q36.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 151856023 - 151948007


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4328487IncompleteBC011921myeloid/lymphoid or mixed-lineage leukemia 3
8860136IncompleteBC151837myeloid/lymphoid or mixed-lineage leukemia 3

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_170606 NP_733751 Q8NEZ4 EC 2.1.1.43  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF264750 AAF74766 Q8NEZ4 EC 2.1.1.43
BC151837 AAI51838 A7MBM6  
AY024361 AAK00583 Q8NEZ4 EC 2.1.1.43
AB040939 BAA96030 Q8NEZ4 EC 2.1.1.43
AK075113 BAC11409 Q8NEZ4 EC 2.1.1.43
AL833924 CAD38780 Q8NEZ4 EC 2.1.1.43
BX640742 CAE45854 Q6N019  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MLL3 NP_733751 M.musculus Mll3 231051 Gene Info NP_001074852 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)