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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. NOS3, Nitric oxide synthase 3 (endothelial cell)
Sequence ID:NM_000603
NM_001160111
NM_001160110
NM_001160109
RefSeqGene ID:NG_011992
Entrez Gene ID:4846
Ensembl ID:ENSG00000164867

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALZHEIMER DISEASEA2M
ACE
APBB2
APP
BLMH
HFE
MPO
PAXIP1
PLAU
SORL1
CEREBRAL INFARCTIONALOX5AP
F2
F5
PRKCH
HYPERTENSIONADD1
AGT
AGTR1
AGTR1
ATP1B1
ATP1B1
CYP3A5
ECE1
GNB3
NOS2
PTGIS
RGS5
RGS5
SELE
HYPERTENSION, PREGNANCY-INDUCEDEPHX1
STOX1

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q36Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 150690891 - 150711257

 Exon Info From UCSC:
NM_000603
NM_001160111
NM_001160110
NM_001160109

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262393Full LengthBC069465nitric oxide synthase 3 (endothelial cell)
30340813Full LengthBC063294nitric oxide synthase 3 (endothelial cell)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000594  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000603 NP_000594   NAD_binding_1
Flavodoxin_1
FAD_binding_1
NO_synthase
NM_001160109 NP_001153581    
NM_001160110 NP_001153582    
NM_001160111 NP_001153583    

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M93718 AAA36364 P29474 EC 1.14.13.39
M95296 AAA36372 P29474 EC 1.14.13.39
S80791 AAD14336 P29474 EC 1.14.13.39
BC063294 AAH63294 P29474 EC 1.14.13.39
BC069465 AAH69465 P29474 EC 1.14.13.39
AF400594 AAK83389 P29474 EC 1.14.13.39
DQ256129 ABB79838 A0S0A6  
DQ256130 ABB79839 A0S0A7  
DQ256131 ABB79840 P29474 EC 1.14.13.39
HQ257992 ADR82746    
AK223636 BAD97356 P29474 EC 1.14.13.39
AK292928 BAF85617 P29474 EC 1.14.13.39
AK315213 BAG37648 P29474 EC 1.14.13.39
AK300390 BAH13275 B7Z6I9  
AK302686 BAH13779 B7Z7Z3  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NOS3 NP_000594 M.musculus Nos3 18127 Gene Info NP_032739 95
R.norvegicus Nos3 24600   NP_068610 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta